abstract：BACKGROUND:In past decade, the treatment of gastric adenocarcinoma has evolved as a result of the publication of two seminal randomized controlled trials. We aimed to examine treatment trends for resectable gastric cancer (stage I-III) using the National Cancer Data Base (NCDB). Our hypothesis was that the use of chemo...

journal_title：Annals of surgical oncology

authors： Raigani S,Hardacre JM,Kim J,Ammori JB

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Whether thyroidectomy for metastases to the thyroid is associated with a survival benefit remains debatable; in general, palliation and disease control are accepted goals in this setting. We evaluated the clinical features and overall survival of patients with thyroid metastasis treated by thyroid resection ...

journal_title：Annals of surgical oncology

authors： Romero Arenas MA,Ryu H,Lee S,Morris LF,Grubbs EG,Lee JE,Perrier ND

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Isolated limb infusion (ILI) is a limb-preserving treatment for in-transit extremity melanoma. The benefit of resecting residual disease after ILI is unclear. METHODS:A multi-institutional experience was analyzed comparing patients who underwent ILI plus resection of residual disease (ILI + RES) versus ILI-...

journal_title：Annals of surgical oncology

authors： Wong J,Chen YA,Fisher KJ,Beasley GM,Tyler DS,Zager JS

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

journal_title：Annals of surgical oncology

authors： Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NCT) for breast cancer might change the number of involved and detected nodes in axillary lymph node dissections (ALND). In this study, we analyzed whether the number of dissected nodes and the lymph node ratio (LNR, defined as the proportion of involved nodes in dissected nodes) wo...

journal_title：Annals of surgical oncology

authors： Chen S,Liu Y,Huang L,Chen CM,Wu J,Shao ZM

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Locally advanced esophageal cancer is often treated with a trimodality approach. While a substantial proportion of such patients initially achieve a clinical complete response (cCR) after chemoradiation, only a small proportion achieve durable control. We analyzed patients who reached cCR after definitive ch...

journal_title：Annals of surgical oncology

authors： Amini A,Ajani J,Komaki R,Allen PK,Minsky BD,Blum M,Xiao L,Suzuki A,Hofstetter W,Swisher S,Gomez D,Liao Z,Lee JH,Bhutani MS,Welsh JW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The effectiveness of perioperative adjuvant chemotherapy for colorectal cancer liver metastasis (CRLM) remains a matter of debate. Despite the lack of clear evidence supporting its effectiveness after curative hepatectomy, adjuvant chemotherapy has been widely used clinically. The purpose of this study was t...

journal_title：Annals of surgical oncology

authors： Hirokawa F,Hayashi M,Miyamoto Y,Asakuma M,Shimizu T,Komeda K,Inoue Y,Uchiyama K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The ToGA trial demonstrated the significant efficacy of trastuzumab in addition to chemotherapy in patients with HER2-positive gastric cancer (GC). Although trastuzumab has become a key drug in breast cancer treatment, resistance to trastuzumab is a major problem in clinical practice. The aim of the current ...

journal_title：Annals of surgical oncology

authors： Eto K,Iwatsuki M,Watanabe M,Ida S,Ishimoto T,Iwagami S,Baba Y,Sakamoto Y,Miyamoto Y,Yoshida N,Baba H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The performance of a mastectomy for the treatment or prophylaxis of breast cancer may have long-term implications for both physical and mental well-being in women. The development of breast numbness and phantom breast sensations following mastectomy is well-known; however, relatively little is known about phy...

journal_title：Annals of surgical oncology

authors： McCarthy CM,Mehrara BJ,Long T,Garcia P,Kropf N,Klassen AF,Cano SJ,Li Y,Hurley K,Scott A,Disa JJ,Cordeiro PG,Pusic AL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) has been shown to reduce many of the long-term complications associated with a traditional axillary lymph node dissection (ALND); however, short-term outcomes have yet to be characterized. This study was designed to identify trends and differences in 30-day outcomes of parti...

journal_title：Annals of surgical oncology

authors： Khavanin N,Gart MS,Berry T,Thornton B,Saha S,Kim JY

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:NIMA-related kinase 2 (NEK2), an enzyme involved in the development and progression of cancer, is abnormally expressed in a wide variety of human cancers, including colorectal cancer (CRC), and is known to have roles in cell division and mitotic regulation through centrosome splitting. We investigated the cl...

journal_title：Annals of surgical oncology

authors： Takahashi Y,Iwaya T,Sawada G,Kurashige J,Matsumura T,Uchi R,Ueo H,Takano Y,Eguchi H,Sudo T,Sugimachi K,Yamamoto H,Doki Y,Mori M,Mimori K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to clarify the priority of nodal dissection in Siewert types II and III adenocarcinoma of the esophagogastric junction (AEG). METHODS:The priority of nodal dissection was evaluated based on the therapeutic value index calculated by multiplying of the frequency of metastasis to e...

journal_title：Annals of surgical oncology

authors： Hasegawa S,Yoshikawa T,Rino Y,Oshima T,Aoyama T,Hayashi T,Sato T,Yukawa N,Kameda Y,Sasaki T,Ono H,Tsuchida K,Cho H,Kunisaki C,Masuda M,Tsuburaya A

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to identify prognostic genes by integrated microarray analysis between comparative genomic hybridization and gene expression with laser microdissection in non-small cell lung cancer (NSCLC). METHODS:Integrated microarray analysis in 11 lung adenocarcinomas was performed, and sever...

journal_title：Annals of surgical oncology

authors： Sakashita H,Inoue H,Akamine S,Ishida T,Inase N,Shirao K,Mori M,Mimori K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Glioma recurrence usually occurs close to the tumor resection margins as a result of residual infiltrating glioma cells. 5-aminolevulinic acid (ALA) fluorescence-guided resection of gliomas has been demonstrated to enhance discrimination of tumor tissue and to improve survival. ALA-based photodynamic therapy...

journal_title：Annals of surgical oncology

authors： Zhao SG,Chen XF,Wang LG,Yang G,Han DY,Teng L,Yang MC,Wang DY,Shi C,Liu YH,Zheng BJ,Shi CB,Gao X,Rainov NG

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Intraperitoneal chemotherapy is used to treat peritoneal surface-spreading malignancies. We sought to determine whether volume and surface area of the intraperitoneal chemotherapy compartments are associated with overall survival and posttreatment glomerular filtration rate (GFR) in malignant peritoneal meso...

journal_title：Annals of surgical oncology

authors： Leinwand JC,Zhao B,Guo X,Krishnamoorthy S,Qi J,Graziano JH,Slavkovic VN,Bates GE,Lewin SN,Allendorf JD,Chabot JA,Schwartz LH,Taub RN

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To determine survival differences for patients undergoing colonic or rectal resection for cancer on the basis of the specific anatomical location of primary tumor. METHODS:A total of 143,747 patients undergoing segmental colectomy, hemicolectomy, anterior resection, or abdominoperineal resection (APER) for ade...

journal_title：Annals of surgical oncology

authors： Bhangu A,Kiran RP,Slesser A,Fitzgerald JE,Brown G,Tekkis P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Oral squamous cell carcinoma (OSCC) is prevalent worldwide, and survival in OSCC has not improved significantly in the last few decades. MicroRNAs have an important regulatory role in oral carcinogenesis. This study investigated the prognostic implications of miR-196 expression and the rs11614913 genotype of...

journal_title：Annals of surgical oncology

authors： Liu CJ,Tsai MM,Tu HF,Lui MT,Cheng HW,Lin SC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The combination of neoadjuvant radiochemotherapy and parenchyma-preserving sleeve resection for lung cancer remains controversial because of potentially increased rate of anastomotic breakdown. We analyzed the effects of applying a decellularized human dermis transplant seeded with autologous fibroblasts in ...

journal_title：Annals of surgical oncology

authors： Roessner E,Vitacolonna M,Schulmeister A,Pilz L,Tsagogiorgas C,Brockmann M,Hohenberger P

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Although esophagectomy traditionally is recommended to perform within 8 weeks after neoadjuvant chemoradiotherapy (nCRT), data from neoadjuvantly treated rectal cancer patients demonstrate that delayed surgery ([8 weeks) can maximize the effect of CRT. Despite these promising data, investigators are concerne...

journal_title：Annals of surgical oncology

authors： Chiu CH,Chao YK,Chang HK,Tseng CK,Chan SC,Liu YH,Chen WH

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Trastuzumab in association with systemic cytotoxic chemotherapy is the standard of care for patients with advanced HER2-positive gastric carcinoma (GC). However, HER2 as a prognostic factor in GC remains controversial. METHODS:HER2 overexpression and amplification was evaluated by immunohistochemistry (IHC)...

journal_title：Annals of surgical oncology

authors： Cho J,Jeong J,Sung J,Sung CO,Kim KM,Park CK,Choi MG,Sohn TS,Bae JM,Kim S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The risk of colorectal cancer (CRC) in chronic kidney disease (CKD) patients relative to the general population is unknown. The aim of this population-based study was to investigate the risk of CRC in patients with CKD. METHODS:The study cohort included patients aged ≥18 years diagnosed with CKD between 200...

journal_title：Annals of surgical oncology

authors： Wu MY,Chang TC,Chao TY,Huang MT,Lin HW

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Survival for Child's A patients with hepatocellular cancer (HCC) and macroscopic vascular invasion (MVI) has been reported as approximately 8.1 months with sorafenib. The role of surgery for these patients remains controversial. METHODS:The records of all patients undergoing resection of HCC at a single cen...

journal_title：Annals of surgical oncology

authors： Roayaie S,Jibara G,Taouli B,Schwartz M

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To assess patterns of uptake and outcomes of laparoscopic colon and rectal cancer surgery in Ontario, and the potential influence of surgical fee incentives instituted on October 1, 2005. METHODS:We used Ontario administrative databases from fiscal years 2002 to 2009. Study outcomes were uptake rates of laparo...

journal_title：Annals of surgical oncology

authors： Simunovic M,Baxter NN,Sutradhar R,Liu N,Cadeddu M,Urbach D

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Oncoplastic surgical techniques offer an option of breast conserving surgery for larger tumors with the use of glandular reshaping to prevent postoperative deformity. A technique for the excision of lower inner quadrant tumors via a V incision is described, the lower-inner quadrant-V (LIQ-V) mammoplasty, and...

journal_title：Annals of surgical oncology

authors： Clough KB,Oden S,Ihrai T,Massey E,Nos C,Sarfati I

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:We postulated that the worse prognosis of melanoma with advancing age reflected more aggressive tumor biology and that in younger patients the prognosis would be more favorable. MATERIALS AND METHODS:The expanded AJCC melanoma staging database contained 11,088 patients with complete data for analysis, inclu...

journal_title：Annals of surgical oncology

authors： Balch CM,Soong SJ,Gershenwald JE,Thompson JF,Coit DG,Atkins MB,Ding S,Cochran AJ,Eggermont AM,Flaherty KT,Gimotty PA,Johnson TM,Kirkwood JM,Leong SP,McMasters KM,Mihm MC Jr,Morton DL,Ross MI,Sondak VK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Based on review of patient data in case conferences over time, we hypothesized that clinically relevant data are omitted in routine soft tissue sarcoma staging. METHODS:We examined subsets of a prospectively collected single institution soft tissue sarcoma database with respect to criteria of the AJCC versi...

journal_title：Annals of surgical oncology

authors： Maki RG,Moraco N,Antonescu CR,Hameed M,Pinkhasik A,Singer S,Brennan MF

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recent studies indicate that women with unilateral breast cancer are choosing contralateral prophylactic mastectomy (CPM) at an increasing rate. There is limited literature evaluating the postoperative complication rates associated with CPM without breast reconstruction. The objective of this study was to co...

journal_title：Annals of surgical oncology

authors： Osman F,Saleh F,Jackson TD,Corrigan MA,Cil T

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:To determine whether satisfaction and health-related quality of life (HR-QoL) differ between women who do and do not undergo contralateral prophylactic mastectomy (CPM) in the setting of implant reconstruction using the BREAST-Q, a validated patient-reported outcome instrument. METHODS:From 2000 to 2007, a tot...

journal_title：Annals of surgical oncology

authors： Koslow S,Pharmer LA,Scott AM,Stempel M,Morrow M,Pusic AL,King TA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The diagnostic phase of care is an anxiety-provoking and stressful experience for the potential breast cancer patient. A multidisciplinary team of breast cancer specialists embarked on a new initiative to pilot a Rapid Diagnosis and Support (RADS) Clinic to coordinate the diagnostic workup and nursing suppor...

journal_title：Annals of surgical oncology

authors： Arnaout A,Smylie J,Seely J,Robertson S,Knight K,Shin S,Ramsey T,Mallick R,Watters J

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:Neuropathic pain (NPP) following breast surgery extends morbidity in the postoperative period. The incidence and etiology of postoperative NPP remains unclear and under-reported in literature. This study aims to define the incidence of neuropathic pain following breast surgery and to identify patient characteri...

journal_title：Annals of surgical oncology

authors： Wilson GC,Quillin RC 3rd,Hanseman DJ,Lewis JD,Edwards MJ,Shaughnessy EA

更新日期：2013-10-01 00:00:00

abstract：:The surveillance of breast cancer patients after potentially curative treatment may result in the identification of locoregional or distant recurrence. While many patients expect frequent imaging studies to monitor for recurrence, there are no data supporting aggressive imaging surveillance beyond mammography. However...

journal_title：Annals of surgical oncology

authors： Leitch AM

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:This multicenter analysis evaluated patient outcome and clinical pathologic features of thymic epithelial tumors after complete surgical resection and adjuvant treatment. METHODS:Histologic classification and clinical staging were performed according to WHO classification and Masaoka staging system, respect...

journal_title：Annals of surgical oncology

authors： Genestreti G,Ampollini L,Burgio MA,Rolli L,Sanna S,Scarpi E,Monti M,Burgio SL,Giannone L,Santo A,Mezzetti M,Casanova C,Buosi R,Rusca M,Amadori D,Gavelli G

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Adaptor proteins, with multimodular structures, can participate in the regulation of various cellular functions. A novel adaptor protein XB130 has been implicated as a substrate and regulator of tyrosine kinase-mediated signaling and in controlling cell proliferation and apoptosis in thyroid and lung cancer ...

journal_title：Annals of surgical oncology

authors： Shiozaki A,Kosuga T,Ichikawa D,Komatsu S,Fujiwara H,Okamoto K,Iitaka D,Nakashima S,Shimizu H,Ishimoto T,Kitagawa M,Nakou Y,Kishimoto M,Liu M,Otsuji E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Previous studies showed conflicting and inconsistent results regarding the effect of anatomic location of the melanoma on sentinel lymph node (SLN) positivity and/or survival. This study was conducted to evaluate and compare the effect of the anatomic locations of primary melanoma on long-term clinical outco...

journal_title：Annals of surgical oncology

authors： Fadaki N,Li R,Parrett B,Sanders G,Thummala S,Martineau L,Cardona-Huerta S,Miranda S,Cheng ST,Miller JR 3rd,Singer M,Cleaver JE,Kashani-Sabet M,Leong SP

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Resection has been the standard of care for patients with solitary hepatocellular carcinoma (HCC). Transarterial embolization and percutaneous ablation are alternative therapies often reserved for suboptimal surgical candidates. Here we compare long-term outcomes of patients with solitary HCC treated with re...

journal_title：Annals of surgical oncology

authors： Elnekave E,Erinjeri JP,Brown KT,Thornton RH,Petre EN,Maybody M,Maluccio MA,Hsu M,Sofocleous CT,Getrajdman GI,Brody LA,Solomon SB,Alago W,Fong Y,Jarnagin WR,Covey AM

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:mTHPC-mediated photodynamic therapy (PDT) is used for treatment of early head and neck squamous cell carcinoma. This study is a retrospective comparison of PDT with transoral surgery in the treatment of early primary squamous cell carcinoma of the oral cavity/oropharynx. METHODS:PDT data were retrieved from...

journal_title：Annals of surgical oncology

authors： de Visscher SA,Melchers LJ,Dijkstra PU,Karakullukcu B,Tan IB,Hopper C,Roodenburg JL,Witjes MJ

更新日期：2013-09-01 00:00:00

abstract：:The number of early gastric cancer (EGC) cases has been increasing because of improved diagnostic procedures. Applications of function-preserving gastric cancer surgery may therefore also be increasing because of its low incidence of lymph node metastasis, excellent survival rates, and the possibility of less-invasive...

journal_title：Annals of surgical oncology

authors： Hiki N,Nunobe S,Kubota T,Jiang X

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the accuracy of breast magnetic resonance imaging (MRI) to predict residual lesion size after neoadjuvant chemotherapy (NAC) and to determine the factors that influence the accuracy of response prediction. METHODS:This study comprised 166 patients who underwent MRI bef...

journal_title：Annals of surgical oncology

authors： Ko ES,Han BK,Kim RB,Ko EY,Shin JH,Hahn SY,Nam SJ,Lee JE,Lee SK,Im YH,Park YH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The utility of sentinel lymph node biopsy (SLNB) for desmoplastic melanoma (DM) is debated. We describe a large single-institution experience with SLNB for DM to determine clinicopathologic factors predictive of SLN metastasis. METHODS:Retrospective review identified 205 patients with DM who underwent SLNB ...

journal_title：Annals of surgical oncology

authors： Han D,Zager JS,Yu D,Zhao X,Walls B,Marzban SS,Rao NG,Sondak VK,Messina JL

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Preoperative differentiation between high-grade malignancy and others (benign or low-grade tumors) is more important than differentiation between malignant and benign tumors for surgical planning, treatment outcome, and prognosis in salivary gland tumors. Fine needle aspiration cytology (FNAC) has a relative...

journal_title：Annals of surgical oncology

authors： Kim BY,Hyeon J,Ryu G,Choi N,Baek CH,Ko YH,Jeong HS

更新日期：2013-07-01 00:00:00